Amino-salicylate drugs are anti-inflammatory agents used to treat some forms of arthritis such as juvvenile rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis; inflammatory bowel disease such as Crohn’s disease, lymphocytic colitis, ulcerative colitis, ulcerative proctitis; and other ailments such as alopecia and uveitis. The production of interleukin-1, platelet-activating factor synthetase, thromboxane synthetase, prostaglandin, and cyclooxygenase are inhibited by 5-aminosalicylates drugs. These drugs inhibit the acute inflammatory response in patients suffering from inflammatory bowel disease. The 5-aminosalicylates drugs reduce the production of immunoglobulin by plasma cells.
Alopecia is a condition where the patient experiences complete or partial hair loss from areas of the body, where it normally grows. Ankylosing spondylitis is a type of spinal arthritis that occurs in younger males, that eventually causes ankylosis of vertebrae and sacroiliac joints. Crohn’s disease is a chronic intestinal disease that causes inflammation, especially in the ileum and colon, and is associated with fistulae and ulcers. Juvenile rheumatoid arthritis causes stiffness and inflammation in joints for more than one and a half months in children under the age of 16 years.
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Lymphocytic colitis is the inflammation of large intestine (colon) that causes persistent watery diarrhea. Psoriatic arthritis a condition that causes red patches and silvery scales on the skin. Rheumatoid arthritis is a chronic disease that causes inflammation in joints resulting in painful immobility and deformity, especially in the ankles, feet, wrists, and fingers. Ulcerative colitis is a condition which causes long-lasting inflammation and ulcers in the digestive tract. Ulcerative proctitis is ulcerative colitis of the rectum. Uveitis is the inflammation of the uvea.
Key players of the global 5-aminosalicylates drugs market include Aspen Australia, Warner Chilcott, Shire Plc, Procter & Gamble Co., Perrigo Company plc, and Pfizer, Inc.
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